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RAB3GAP2 Monoklonaler Antikörper

RAB3GAP2 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

3A4A1

Kat-Nr. : 66648-1-PBS

Synonyme

DKFZp434D245, FLJ14579, KIAA0839, p150, Rab3 GAP p150, Rab3 GAP regulatory subunit, RAB3 GAP150, RAB3GAP150, RAB3GAP2, RGAP iso

Filter:
  • Western Blot (WB) analysis of various lysates using RAB3GAP2 Monoclonal antibody (66648-1-Ig)

    WB analysis using 66648-1-Ig (same clone as 66648-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 66648-1-Ig (RAB3GAP2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66648-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

66648-1-PBS bindet in WB, Indirect ELISA RAB3GAP2 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG2a
Klonalität Monoklonal
Typ Antikörper
Immunogen RAB3GAP2 fusion protein Ag20254
Vollständiger Name RAB3 GTPase activating protein subunit 2 (non-catalytic)
Berechnetes Molekulargewicht 1393 aa, 156 kDa
Beobachtetes Molekulargewicht 150 kDa
GenBank-ZugangsnummerBC146760
Gene symbol RAB3GAP2
Gene ID (NCBI) 25782
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

RAB3GAP2, also known as RAB3-GAP150, belongs to the Rab3-GAP regulatory subunit family. Rab3 GAP consists of two subunits: the catalytic subunit p130 and the noncatalytic subunit p150. Rab3 GAP is ubiquitously expressed and enriched in the synaptic soluble fraction of brain, consistent with it having a key role in neurodevelopment. RAB3-GAP150 forms the Rab3 GTPase-activating complex with RAB3-GAP130,where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. Defects in RAB3-GAP150 are the cause of Martsolf and Warburg Micro syndrome.