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RABGGTA Rekombinanter Antikörper

RABGGTA Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251036C3

Kat-Nr. : 86386-3-PBS

Synonyme

EC:2.5.1.60, Geranylgeranyl transferase type-2 subunit alpha, Rab geranyl-geranyltransferase subunit alpha, Rab GG transferase alpha, Rab GGTase alpha

Filter:
  • Western Blot (WB) analysis of various lysates using RABGGTA Recombinant antibody (86386-3-RR)

    WB analysis using 86386-3-RR (same clone as 86386-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86386-3-RR (RABGGTA antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86386-3-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86386-3-RR

    Affinity and Kinetic Characterization of 86386-3-RR

    Biolayer interferometry (BLl) kinetic assays of 86386-3-RR against Human RABGGTA were performed. The affinity constant is below 1 pM.

Geprüfte Anwendungen

Produktinformation

86386-3-PBS bindet in WB, Indirect ELISA RABGGTA und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen RABGGTA fusion protein Ag5923
Vollständiger Name Rab geranylgeranyltransferase, alpha subunit
Berechnetes Molekulargewicht 65 kDa
Beobachtetes Molekulargewicht60~65 kDa
GenBank-ZugangsnummerBC003093
Gene symbol RABGGTA
Gene ID (NCBI) 5875
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

GGTase II (RAB geranylgeranyl transferase, RABGGTase) is a heterodimer composed of tightly bound α- and β-subunits, which belongs to the Ras superfamily of small monomeric GTPases. RABGGTase is extensively involved in intracellular membrane trafficking of membrane-bound organelles and vesicles and specifically catalyses the covalent attachment of GGPP to the cysteine of a carboxyl-terminal CC or CXC motif of RAB proteins (PMID 11136552, 10737774, 35961942).