RAC2 Monoklonaler Antikörper

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• KD/KO Validated

RAC2 Monoklonal Antikörper für WB, IHC, ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, ELISA

Konjugation

Unkonjugiert

CloneNo.

4C2H6

Kat-Nr. : 60077-1-PBS

Synonyme

4C2H6, Gx, HSPC022, p21 Rac2, p21-Rac2

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• 

  WB analysis using 60077-1-Ig (same clone as 60077-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 60077-1-Ig (RAC2 antibody) at dilution of 1:20000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60077-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human tonsillitis using 60077-1-Ig (same clone as 60077-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 60077-1-Ig (RAC2 antibody) at dilution of 1:8000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60077-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human tonsillitis using 60077-1-Ig (same clone as 60077-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 60077-1-Ig (RAC2 antibody) at dilution of 1:8000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60077-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human tonsillitis using 60077-1-Ig (same clone as 60077-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 60077-1-Ig (RAC2 antibody) at dilution of 1:8000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60077-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human tonsillitis using 60077-1-Ig (same clone as 60077-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 60077-1-Ig (RAC2 antibody) at dilution of 1:8000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 60077-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

60077-1-PBS bindet in WB, IHC, ELISA RAC2 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: RAC2 fusion protein Ag1202
• Vollständiger Name: ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2)
• Berechnetes Molekulargewicht: 21 kDa
• Beobachtetes Molekulargewicht: 21 kDa
• GenBank-Zugangsnummer: BC001485
• Gene symbol: RAC2
• Gene ID (NCBI): 5880
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

RAC2, also named as GX, belongs to the small GTPase superfamily and Rho family. RAC2 is a plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as secretory processes, phagocytose of apoptotic cells and epithelial cell polarization. RAC2 augments the production of reactive oxygen species (ROS) by NADPH oxidase. Defects in RAC2 are the cause of neutrophil immunodeficiency syndrome.