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RAD17 Monoklonaler Antikörper

RAD17 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1F12D8

Kat-Nr. : 68539-1-PBS

Synonyme

CCYC, FLJ41520, HRAD17, R24L, RAD17, RAD17 homolog (S. pombe), RAD17SP, RAD24, RF C/activator 1 homolog

Filter:
  • Western Blot (WB) analysis of various lysates using RAD17 Monoclonal antibody (68539-1-Ig)

    WB analysis using 68539-1-Ig (same clone as 68539-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 68539-1-Ig (RAD17 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68539-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

68539-1-PBS bindet in WB, Indirect ELISA RAD17 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen RAD17 fusion protein Ag4348
Vollständiger Name RAD17 homolog (S. pombe)
Berechnetes Molekulargewicht 681 aa, 71 kDa
Beobachtetes Molekulargewicht70-80 kDa
GenBank-ZugangsnummerBC032304
Gene symbol RAD17
Gene ID (NCBI) 5884
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Rad17, a component of the checkpoint clamp loader complex (RAD17/RFC), was originally initially identified as a DNA damage checkpoint protein. Rad17 participates in cell cycle control and DNA damage repair. Rad17 phosphorylation by ATR (ataxia telangiectasia mutated and Rad3-related) kinase is indispensable for the recruitment of Claspin and the activation of Chk1 in response to genotoxic stress.