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RAD23A Polyklonaler Antikörper

RAD23A Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 11364-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of mouse testis tissue using RAD23A Polyclonal antibody (11364-1-AP)

    WB analysis of mouse testis using 11364-1-AP (same clone as 11364-1-PBS)

    mouse testis tissue were subjected to SDS PAGE followed by western blot with 11364-1-AP (RAD23A antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11364-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of mouse testis tissue using RAD23A Polyclonal antibody (11364-1-AP)

    WB analysis of mouse testis using 11364-1-AP (same clone as 11364-1-PBS)

    mouse testis tissue were subjected to SDS PAGE followed by western blot with 11364-1-AP (RAD23A antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11364-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

11364-1-PBS bindet in WB, Indirect ELISA RAD23A und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen RAD23A fusion protein Ag1907
Vollständiger Name RAD23 homolog A (S. cerevisiae)
Berechnetes Molekulargewicht 40 kDa
Beobachtetes Molekulargewicht 55 kDa
GenBank-ZugangsnummerBC014026
Gene symbol RAD23A
Gene ID (NCBI) 5886
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

RAD23A, also named as HHR23A, belongs to the RAD23 family. It is a multiubiquitin chain receptor involved in modulation of proteasomal degradation. RAD23A binds to 'Lys-48'-linked polyubiquitin chains in a length-dependent manner and with a lower affinity to 'Lys-63'-linked polyubiquitin chains. It is proposed to be capable to bind simultaneously to the 26S proteasome and to polyubiquitinated substrates and to deliver ubiquitinated proteins to the proteasome. It is involved in nucleotide excision repair and is thought to be functional equivalent for RAD23B in global genome nucleotide excision repair (GG-NER) by association with XPC. In vitro, the XPC:RAD23A dimer has NER activity. Can stabilize XPC. It is also involved in vpr-dependent replication of HIV-1 in non-proliferating cells and primary macrophages and is required for the association of HIV-1 vpr with the host proteasome. This antibody is a rabbit polyclonal antibody raised against full length RAD23A of human origin.