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RAG1 Polyklonaler Antikörper

RAG1 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 20977-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using RAG1 Polyclonal antibody (20977-1-AP)

    WB analysis using 20977-1-AP (same clone as 20977-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 20977-1-AP (RAG1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20977-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

20977-1-PBS bindet in WB, Indirect ELISA RAG1 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name recombination activating gene 1
Berechnetes Molekulargewicht 119 kDa
Beobachtetes Molekulargewicht110-120 kDa
GenBank-ZugangsnummerNM_000448
Gene symbol RAG1
Gene ID (NCBI) 5896
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Recombination-activating gene (RAG) proteins include RAG1 and RAG2, which are crucial for Ig and T lymphocyte receptor (TCR) fragment rearrangement and are responsible for DNA recognition and cleavage at specific sequences. Mutations in RAG1 result in the complete or partial loss of recombinant enzyme activity, in unbalanced variable-diversity-joining (V(D)J) recombination, and in the impairment of T and B lymphocyte development at the early stages.