RAG1 Monoklonaler Antikörper

RAG1 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

3A1A4

Kat-Nr. : 68591-1-PBS

Synonyme

RAG 1, RAG1, RNF74

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  WB analysis using 68591-1-Ig (same clone as 68591-1-PBS)

  mouse thymus tissue were subjected to SDS PAGE followed by western blot with 68591-1-Ig (RAG1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 68591-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

68591-1-PBS bindet in WB, Indirect ELISA RAG1 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Maus / IgG2b
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: RAG1 fusion protein Ag30192
• Vollständiger Name: recombination activating gene 1
• Berechnetes Molekulargewicht: 119 kDa
• Beobachtetes Molekulargewicht: 110-119 kDa
• GenBank-Zugangsnummer: NM_000448
• Gene symbol: RAG1
• Gene ID (NCBI): 5896
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Recombination-activating gene (RAG) proteins include RAG1 and RAG2, which are crucial for Ig and T lymphocyte receptor (TCR) fragment rearrangement and are responsible for DNA recognition and cleavage at specific sequences. Mutations in RAG1 result in the complete or partial loss of recombinant enzyme activity, in unbalanced variable-diversity-joining (V(D)J) recombination, and in the impairment of T and B lymphocyte development at the early stages.