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RANK/TNFRSF11A Polyklonaler Antikörper

RANK/TNFRSF11A Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 55293-1-PBS

Synonyme

TNFRSF11A, TNR11, Receptor activator of NF-KB, Receptor activator of NF KB, RANK

Filter:
  • Western Blot (WB) analysis of various lysates using RANK/TNFRSF11A Polyclonal antibody (55293-1-AP)

    WB analysis using 55293-1-AP (same clone as 55293-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 55293-1-AP (RANK antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55293-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

55293-1-PBS bindet in WB, Indirect ELISA RANK/TNFRSF11A und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name tumor necrosis factor receptor superfamily, member 11a, NFKB activator
Berechnetes Molekulargewicht 66 kDa
Beobachtetes Molekulargewicht80-90 kDa
GenBank-ZugangsnummerNM_003839
Gene symbol TNFRSF11A
Gene ID (NCBI) 8792
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Tumor necrosis factor receptor superfamily member 11A (TNFRSF11A, also known as RANK, CD265, and ODFR) is the signaling receptor essential for osteoclast differentiation factor-mediated osteoclastogenesis and is involved in the regulation of interactions between T-cells and dendritic cells (PMID: 9878548). The RANK/RANKL/OPG system is a key regulator in bone resorption, and its dysregulation can lead to pathological bone loss (PMID: 37893470).