RARG Rekombinanter Antikörper

RARG Rekombinant Antikörper für WB, Sandwich ELISA, Indirect ELISA, Sample test

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Sandwich ELISA, Indirect ELISA, Sample test

Konjugation

Unkonjugiert

CloneNo.

250399C1

Kat-Nr. : 86098-1-PBS

Synonyme

NR1B3, RAR gamma, RARC, RAR-gamma, Retinoic acid receptor gamma

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  WB analysis using 86098-1-RR (same clone as 86098-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 86098-1-RR (RARG antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86098-1-PBS in a different storage buffer formulation.

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  Sandwich ELISA standard curve of MP02317-1

  Sandwich ELISA standard curve of MP02317-1, Human RARG Recombinant Matched Antibody Pair - PBS only. 86098-2-PBS was coated to a plate as the capture antibody and incubated with serial dilutions of standard Ag1991. 86098-1-PBS was HRP conjugated as the detection antibody. Range: 46.9-3000 pg/mL.

• 

  Sample test of MP02317-1

  The mean RARG concentration was determined to be 3.4 ng/mL in MCF-7 cell extract based on a 1.2 mg/mL extract load.

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Geprüfte Anwendungen

Produktinformation

86098-1-PBS bindet in WB, Sandwich ELISA, Indirect ELISA, Sample test RARG und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: RARG fusion protein Ag1991
• Vollständiger Name: retinoic acid receptor, gamma
• Berechnetes Molekulargewicht: 454 aa, 50 kDa
• Beobachtetes Molekulargewicht: 50-60kDa
• GenBank-Zugangsnummer: BC019098
• Gene symbol: RARG
• Gene ID (NCBI): 5916
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Retinoic acid receptors (RARs) are nuclear hormone receptors that act as ligand-dependent transcriptional regulators. In their liganded state, RARs activate transcription, whereas in their nonliganded form, they repress transcription of their target genes. RARs have numerous target genes, which have retinoic response elements in their promoter regions (PMID:17574023). RARG is a member of the retinoid acid receptor (RAR) family, along with RARA, which is known to be involved PML/RARA fusion of acute promyelocytic leukemia, and RARB. and rearrangement that conferred to leukemic cells acute promyelocytic leukemia-like morphologic and immunophenotypic features (PMID:20935257).