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RARS2 Polyklonaler Antikörper

RARS2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 16079-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using RARS2 Polyclonal antibody (16079-1-AP)

    WB analysis using 16079-1-AP (same clone as 16079-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 16079-1-AP (RARS2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 16079-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

16079-1-PBS bindet in WB, Indirect ELISA RARS2 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen RARS2 fusion protein Ag9074
Vollständiger Name arginyl-tRNA synthetase 2, mitochondrial
Berechnetes Molekulargewicht 578 aa, 66 kDa
Beobachtetes Molekulargewicht66-70 kDa
GenBank-ZugangsnummerBC010420
Gene symbol RARS2
Gene ID (NCBI) 57038
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

RARS2 encodes the mitochondrial arginyl transfer RNA (tRNA) synthetase, an enzyme which belongs to the group of mitochondrial aminoacyl tRNA synthetases. These nuclear encoded mitochondrial proteins play a key role in mitochondrial protein translation by catalyzing the attachment of amino acids to their cognate tRNA molecules . Variants in RARS2 gene are associated with pontocerebellar hypoplasia type 6 (PCH6; MIM 611523), a rare mitochondrial encephalopathy with phenotype characterized by early onset seizures, profound developmental delay, and progressive pontocerebellar atrophy.(PMID: 27769281, PMID: 33209735)