• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

RASA2 Polyklonaler Antikörper

RASA2 Polyklonal Antikörper für IF/ICC, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IF/ICC, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31586-1-PBS

Synonyme

GAP1M, RAS p21 protein activator 2, RASGAP

Filter:
  • Immunoprecipitation (IP) experiment of Jurkat cells using RASA2 Polyclonal antibody (31586-1-AP)

    IP experiment of Jurkat using 31586-1-AP (same clone as 31586-1-PBS)

    IP result of anti-RASA2 (IP:31586-1-AP, 4ug; Detection:31586-1-AP 1:1000) with Jurkat cells lysate 1920 ug. This data was developed using the same antibody clone with 31586-1-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of A431 cells using RASA2 Polyclonal antibody (31586-1-AP)

    IP experiment of A431 using 31586-1-AP (same clone as 31586-1-PBS)

    IP result of anti-RASA2 (IP:31586-1-AP, 4ug; Detection:31586-1-AP 1:1000) with A431 cells lysate 1120 ug. This data was developed using the same antibody clone with 31586-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of A431 cells using RASA2 Polyclonal antibody (31586-1-AP)

    IF Staining of A431 using 31586-1-AP (same clone as 31586-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed A431 cells using RASA2 antibody (31586-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 31586-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

31586-1-PBS bindet in IF/ICC, IP, Indirect ELISA RASA2 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen RASA2 fusion protein Ag35885
Vollständiger Name RAS p21 protein activator 2
Berechnetes Molekulargewicht96kDa
Beobachtetes Molekulargewicht 97 kDa
GenBank-ZugangsnummerNM_001303245
Gene symbol RASA2
Gene ID (NCBI) 5922
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Ras GTPase-activating protein 2 (RASA2) is also named GAP1M and RASGAP. RASA2 was a critical RAS-specific GAP, inhibition of which permitted increased proliferation following TCR stimulation under conditions of immunosuppression (PMID: 37858490). RASA2 was identified as an inhibitor of RAS signaling in multiple human tumors, including melanoma, where inactivating RASA2 mutations have been found (PMID: 26502337). RASA2 is also one of the genes mutated in Noonan syndrome, a Rasopathy associated with developmental defects and elevated RAS activity (PMID: 25049390). RASA2 is expressed in both CD4+ and CD8+ T cells (PMID: 36002574).