RAVER2 Polyklonaler Antikörper

RAVER2 Polyklonal Antikörper für IP, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IP, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32025-1-AP

Synonyme

KIAA1579, Protein raver-2, Ribonucleoprotein PTB-binding 2

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  IP experiment of HEK-293T using 32025-1-AP

  IP result of anti-RAVER2 (IP:32025-1-AP, 4ug; Detection:32025-1-AP 1:2000) with HEK-293T cells lysate 2200 ug.

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Geprüfte Anwendungen

• Erfolgreiche IP: HEK-293T-Zellen

Empfohlene Verdünnung

• Immunpräzipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

32025-1-AP bindet in IP, ELISA RAVER2 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: RAVER2 fusion protein Ag36879
• Vollständiger Name: ribonucleoprotein, PTB-binding 2
• Berechnetes Molekulargewicht: 74/72 kDa
• Beobachtetes Molekulargewicht: 75 kDa
• GenBank-Zugangsnummer: BC065303
• Gene symbol: RAVER2
• Gene ID (NCBI): 55225
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Raver2 was identified as a novel member of the hnRNP family based on sequence homology within three RNA recognition motifs and its general domain organization reminiscent of the previously described raver1 protein. Like raver1, raver2 contains two putative nuclear localization signals and a potential nuclear export sequence, and also displays nucleo-cytoplasmic shuttling in a heterokaryon assay. In glia cells and neurons, raver2 localizes to the nucleus. Moreover, the protein interacts with polypyrimidine tract binding protein (PTB) suggesting that it may participate in PTB-mediated nuclear functions. In contrast to ubiquitously expressed raver1, raver2 exerts a distinct spatio-temporal expression pattern during embryogenesis and is essentially restricted to brain, lung, and kidney in the adult mouse (PMID: 16051233).