RAVER2 Polyklonaler Antikörper

RAVER2 Polyklonal Antikörper für IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 32025-1-PBS

Synonyme

KIAA1579, Protein raver-2, Ribonucleoprotein PTB-binding 2



Geprüfte Anwendungen

Produktinformation

32025-1-PBS bindet in IP, Indirect ELISA RAVER2 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen RAVER2 fusion protein Ag36879
Vollständiger Name ribonucleoprotein, PTB-binding 2
Berechnetes Molekulargewicht74/72 kDa
Beobachtetes Molekulargewicht75 kDa
GenBank-ZugangsnummerBC065303
Gene symbol RAVER2
Gene ID (NCBI) 55225
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Raver2 was identified as a novel member of the hnRNP family based on sequence homology within three RNA recognition motifs and its general domain organization reminiscent of the previously described raver1 protein. Like raver1, raver2 contains two putative nuclear localization signals and a potential nuclear export sequence, and also displays nucleo-cytoplasmic shuttling in a heterokaryon assay. In glia cells and neurons, raver2 localizes to the nucleus. Moreover, the protein interacts with polypyrimidine tract binding protein (PTB) suggesting that it may participate in PTB-mediated nuclear functions. In contrast to ubiquitously expressed raver1, raver2 exerts a distinct spatio-temporal expression pattern during embryogenesis and is essentially restricted to brain, lung, and kidney in the adult mouse (PMID: 16051233).