RAVER2 Polyklonaler Antikörper
RAVER2 Polyklonal Antikörper für IP, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
IP, Indirect ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 32025-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
32025-1-PBS bindet in IP, Indirect ELISA RAVER2 und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | RAVER2 fusion protein Ag36879 |
| Vollständiger Name | ribonucleoprotein, PTB-binding 2 |
| Berechnetes Molekulargewicht | 74/72 kDa |
| Beobachtetes Molekulargewicht | 75 kDa |
| GenBank-Zugangsnummer | BC065303 |
| Gene symbol | RAVER2 |
| Gene ID (NCBI) | 55225 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Raver2 was identified as a novel member of the hnRNP family based on sequence homology within three RNA recognition motifs and its general domain organization reminiscent of the previously described raver1 protein. Like raver1, raver2 contains two putative nuclear localization signals and a potential nuclear export sequence, and also displays nucleo-cytoplasmic shuttling in a heterokaryon assay. In glia cells and neurons, raver2 localizes to the nucleus. Moreover, the protein interacts with polypyrimidine tract binding protein (PTB) suggesting that it may participate in PTB-mediated nuclear functions. In contrast to ubiquitously expressed raver1, raver2 exerts a distinct spatio-temporal expression pattern during embryogenesis and is essentially restricted to brain, lung, and kidney in the adult mouse (PMID: 16051233).

