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RBM47 Rekombinanter Antikörper

RBM47 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250436D5

Kat-Nr. : 86009-2-PBS

Synonyme

NET18, RNA binding motif protein 47, RNA binding protein 47, RNA-binding motif protein 47, RNA-binding protein 47

Filter:
  • Western Blot (WB) analysis of various lysates using RBM47 Recombinant antibody (86009-2-RR)

    WB analysis using 86009-2-RR (same clone as 86009-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86009-2-RR (RBM47 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86009-2-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86009-2-RR

    Affinity and Kinetic Characterization of 86009-2-RR

    Biolayer interferometry (BLl) kinetic assays of 86009-2-RR against Human RBM47 were performed. The affinity constant is 1.40 nM.

Geprüfte Anwendungen

Produktinformation

86009-2-PBS bindet in WB, Indirect ELISA RBM47 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen RBM47 fusion protein Ag20984
Vollständiger Name RNA binding motif protein 47
Berechnetes Molekulargewicht 593 aa, 64 kDa
Beobachtetes Molekulargewicht 64 kDa
GenBank-ZugangsnummerBC126261
Gene symbol RBM47
Gene ID (NCBI) 54502
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

RBM47, also known as RNA-binding motif protein 47 or RNA-binding protein 47, is a vertebrate-conserved RBP containing three RNA-recognition motifs (RRMs) that perform multifaceted roles in RNA editing, early embryonic development, and cancer.Recent studies suggest that RBM47 functions as a tumor suppressor. It has been shown to suppress the progression of breast and colon cancers. RBM47 represents a molecular switch of cell fate decisions that functions as a regulator of the p53/p21-signaling axis. (PMID: 34499322, PMID: 31511650)