RBM48 Polyklonaler Antikörper

RBM48 Polyklonal Antikörper für WB, IF/ICC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IF/ICC, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 28307-1-AP

Synonyme

C7orf64, UPF0712 protein C7orf64, RNA-binding protein 48, HSPC304

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  WB analysis using 28307-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 28307-1-AP (RBM48 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

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  IF Staining of A431 using 28307-1-AP

  Immunofluorescent analysis of (4% PFA) fixed A431 cells using RBM48 antibody (28307-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2).

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Maushirngewebe, Maushodengewebe
• Erfolgreiche Detektion in IF/ICC: A431-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:2000
• Immunfluoreszenz (IF)/ICC: IF/ICC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

28307-1-AP bindet in WB, IF/ICC, ELISA RBM48 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: RBM48 fusion protein Ag27277
• Vollständiger Name: chromosome 7 open reading frame 64
• Beobachtetes Molekulargewicht: 40 kDa
• GenBank-Zugangsnummer: BC104865
• Gene symbol: C7orf64
• Gene ID (NCBI): 84060
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

RBM48 (RNA Binding Motif Protein 48) is a gene encoding an RNA-binding protein, belonging to the RNA-binding motif protein family, which plays an important role in the splicing process of U12-type introns. Deletion of RBM48 leads to an increase in the retention of U12-type introns, which affects cell differentiation and proliferation. And mutations in RBM48 are associated with a variety of diseases. For example, U12 intron splicing defects are associated with myelodysplastic syndromes (MDS) and may increase the risk of acute myeloid leukemia (AML). RBM48 may serve as a prognostic marker in certain cancers, such as renal smoky cell carcinoma, renal clear cell carcinoma, and hepatocellular carcinoma.