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RBM48 Polyklonaler Antikörper

RBM48 Polyklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 28307-1-PBS

Synonyme

C7orf64, UPF0712 protein C7orf64, RNA-binding protein 48, HSPC304

Filter:
  • Western Blot (WB) analysis of various lysates using RBM48 Polyclonal antibody (28307-1-AP)

    WB analysis using 28307-1-AP (same clone as 28307-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 28307-1-AP (RBM48 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28307-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of A431 cells using RBM48 Polyclonal antibody (28307-1-AP)

    IF Staining of A431 using 28307-1-AP (same clone as 28307-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed A431 cells using RBM48 antibody (28307-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 28307-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

28307-1-PBS bindet in WB, IF/ICC, Indirect ELISA RBM48 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen RBM48 fusion protein Ag27277
Vollständiger Name chromosome 7 open reading frame 64
Beobachtetes Molekulargewicht40 kDa
GenBank-ZugangsnummerBC104865
Gene symbol C7orf64
Gene ID (NCBI) 84060
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

RBM48 (RNA Binding Motif Protein 48) is a gene encoding an RNA-binding protein, belonging to the RNA-binding motif protein family, which plays an important role in the splicing process of U12-type introns. Deletion of RBM48 leads to an increase in the retention of U12-type introns, which affects cell differentiation and proliferation. And mutations in RBM48 are associated with a variety of diseases. For example, U12 intron splicing defects are associated with myelodysplastic syndromes (MDS) and may increase the risk of acute myeloid leukemia (AML). RBM48 may serve as a prognostic marker in certain cancers, such as renal smoky cell carcinoma, renal clear cell carcinoma, and hepatocellular carcinoma.