• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

RBPJ Rekombinanter Antikörper

RBPJ Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

243044G4

Kat-Nr. : 85676-3-PBS

Synonyme

CBF 1, CBF1, CBF-1, csl, IGKJRB

Filter:
  • Western Blot (WB) analysis of various lysates using RBPJ Recombinant antibody (85676-3-RR)

    WB analysis using 85676-3-RR (same clone as 85676-3-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 85676-3-RR (RBPJ antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85676-3-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

85676-3-PBS bindet in WB, Indirect ELISA RBPJ und zeigt Reaktivität mit human, Ratten

Getestete Reaktivität human, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen RBPJ fusion protein Ag32552
Vollständiger Name recombination signal binding protein for immunoglobulin kappa J region
Berechnetes Molekulargewicht 56 kDa
Beobachtetes Molekulargewicht~60 kDa
GenBank-ZugangsnummerBC064976
Gene symbol RBPJ
Gene ID (NCBI) 3516
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

RBPJ, also named as IGKJRB, IGKJRB1, RBPJK, RBPSUH, NY-REN-30, CBF-1 and CSL, belongs to the Su(H) family. It is a transcriptional regulator that plays a central role in Notch signaling, a signaling pathway involved in cell-cell communication that regulates a broad spectrum of cell-fate determinations. RBPJ acts as a transcriptional repressor when it is not associated with Notch proteins. It is specifically binds to the immunoglobulin kappa-type J segment recombination signal sequence. RBPJ binds to the Runx3 promoter in the atrioventricular canal in vivo, and inhibition of Notch reduces RUNX3 expression in the cardiac cushion of embryonic hearts.