RC3H1 Rekombinanter Antikörper

RC3H1 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241046G10

Kat-Nr. : 84323-1-PBS

Synonyme

241046G10, KIAA2025, RING finger protein 198, RNF198, ROQUIN

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  WB analysis using 84323-1-RR (same clone as 84323-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84323-1-RR (RC3H1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84323-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

84323-1-PBS bindet in WB, Indirect ELISA RC3H1 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: ring finger and CCCH-type zinc finger domains 1
• Beobachtetes Molekulargewicht: 130-140 kDa
• GenBank-Zugangsnummer: NM_172071
• Gene symbol: RC3H1
• Gene ID (NCBI): 149041
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Roquin-1 (Rc3h1) is an E3 ubiquitin ligase originally discovered in a mutational screen for genetic factors contributory to systemic lupus erythematosus-like symptoms in mice. A single base pair mutation in the Rc3h1 gene resulted in the manifestation of autoantibody production and sustained immunological inflammation characterized by excessive T follicular helper cell activation and formation of germinal centers. (PMID: 26673963)