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RCAS1 Monoklonaler Antikörper

RCAS1 Monoklonal Antikörper für ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IF, ELISA

Konjugation

Unkonjugiert

Publikationen(1)

CloneNo.

4H8A12

Kat-Nr. : 66170-1-Ig

Synonyme

EBAG9, Estrogen receptor-binding fragment-associated gene 9 protein, EBAG 9, EB9, Cancer-associated surface antigen RCAS1

Geprüfte Anwendungen

Veröffentlichte Anwendungen

WBSee 1 publications below
IFSee 1 publications below

Produktinformation

66170-1-Ig bindet in WB, IF, ELISA RCAS1 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
In Publikationen genannte ReaktivitätMaus
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen RCAS1 fusion protein Ag2905
Vollständiger Name estrogen receptor binding site associated, antigen, 9
Berechnetes Molekulargewicht 213 aa, 24 kDa
Beobachtetes Molekulargewicht 34 kDa
GenBank-ZugangsnummerBC017729
Gene symbol RCAS1
Gene ID (NCBI) 9166
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS with 0.02% sodium azide and 50% glycerol
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Estrogen receptor-binding fragment-associated antigen 9 (EBAG9) gene was identified as an estrogen-responsive gene. The gene product, receptor-binding cancer antigen expressed on SiSo cells (RCAS1), is associated with aggressive characteristics and poor overall survival for 15 different human malignancies. The correlation between RCAS1 expression and several clinicopathological variables, including tumor size, clinical stage, invasion depth and lymph node metastasis highlights this molecule's clinical significance. Expression of RCAS1 in tumor cells plays an important role in evasion from host immune system resulting tumor progression, invasion and metastasis. Further exploration of RCAS1 biological function will facilitate development of novel therapeutic strategies that target RCAS1.

Publikationen

SpeciesApplicationTitle
mouseWB,IF

Mol Med Rep

RCAS1 increases cell morphological changes in murine fibroblasts by reducing p38 phosphorylation

Authors - Takuya Nishinakagawa
View Article