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RFX6 Polyklonaler Antikörper

RFX6 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 22551-1-PBS

Synonyme

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  • Western Blot (WB) analysis of Caco-2 cells using RFX6 Polyclonal antibody (22551-1-AP)

    WB analysis of Caco-2 using 22551-1-AP (same clone as 22551-1-PBS)

    Caco-2 cells were subjected to SDS PAGE followed by western blot with 22551-1-AP (RFX6 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22551-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of Caco-2 cells using RFX6 Polyclonal antibody (22551-1-AP)

    WB analysis of Caco-2 using 22551-1-AP (same clone as 22551-1-PBS)

    Caco-2 cells were subjected to SDS PAGE followed by western blot with 22551-1-AP (RFX6 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22551-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

22551-1-PBS bindet in WB, Indirect ELISA RFX6 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen RFX6 fusion protein Ag18235
Vollständiger Name regulatory factor X, 6
Berechnetes Molekulargewicht 928 aa, 102 kDa
Beobachtetes Molekulargewicht 102 kDa
GenBank-ZugangsnummerBC039248
Gene symbol RFX6
Gene ID (NCBI) 222546
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The RFX proteins represent an essential class II transcription factor family that share several conserved regions, including a centrally located DNA-binding domain (DBD) and a C-terminal D region that facilitates dimerization. RFX6, also known as RFXDC1, is a 928 amino acid nuclear protein that, via interactions with other RFX proteins, can bind DNA and is thought to activate the transcription of target genes. RFX6 is specifically expressed in pancreas, small intestine and colon. Mutations in the gene encoding RFX6 is the cause of the Mitchell-Riley syndrome (MIRIS), which is characterized by neonatal diabetes, duodenal and jejunal atresia, a hypoplastic or annular pancreas and absent gallbladder.