RGNEF Rekombinanter Antikörper

RGNEF Rekombinant Antikörper für WB, Cytometric bead array, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Cytometric bead array, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241975E4

Kat-Nr. : 84570-2-PBS

Synonyme

ARHGEF28, p190-RhoGEF, p190RhoGEF, p190 RhoGEF, ARG28

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  WB analysis using 84570-2-RR (same clone as 84570-2-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84570-2-RR (RGNEF antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84570-2-PBS in a different storage buffer formulation.

• 

  Cytometric bead array standard curve of MP01414-1

  Cytometric bead array standard curve of MP01414-1, RGNEF Recombinant Matched Antibody Pair, PBS Only. Capture antibody: 84570-2-PBS. Detection antibody: 84570-1-PBS. Standard: Ag10915. Range: 0.469-60 ng/mL.

• 

  Affinity and Kinetic Characterization of 84570-2-RR

  Biolayer interferometry (BLl) kinetic assays of 84570-2-RR against Human RGNEF were performed. The affinity constant is below 1 pM.

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Geprüfte Anwendungen

Produktinformation

84570-2-PBS bindet in WB, Cytometric bead array, Indirect ELISA RGNEF und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: RGNEF fusion protein Ag10915
• Vollständiger Name: Rho-guanine nucleotide exchange factor
• Berechnetes Molekulargewicht: 192 kDa
• Beobachtetes Molekulargewicht: 192 kDa
• GenBank-Zugangsnummer: BC012946
• Gene symbol: RGNEF
• Gene ID (NCBI): 64283
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ARHGEF28, also known as RGNEF or p190RhoGEF, is a 190 kDa RNA binding protein (RBP) that contains a Dbl/PH domain capable of RhoA activation. ARHGEF28 interacts with low molecular weight neurofilament mRNA and may be involved in the formation of amyotrophic lateral sclerosis neurofilament aggregates.