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RGS13 Polyklonaler Antikörper

RGS13 Polyklonal Antikörper für IHC, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IHC, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 12396-1-PBS

Synonyme

Regulator of G-protein signaling 13

Filter:
  • Immunoprecipitation (IP) experiment of Ramos cells using RGS13 Polyclonal antibody (12396-1-AP)

    IP experiment of Ramos using 12396-1-AP (same clone as 12396-1-PBS)

    IP result of anti-RGS13 (IP:12396-1-AP, 4ug; Detection:12396-1-AP 1:500) with Ramos cells lysate 1680 ug. This data was developed using the same antibody clone with 12396-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human lymphoma tissue using RGS13 Polyclonal antibody (12396-1-AP)

    IHC staining of human lymphoma using 12396-1-AP (same clone as 12396-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lymphoma tissue slide using 12396-1-AP (RGS13 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 12396-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

12396-1-PBS bindet in IHC, IP, Indirect ELISA RGS13 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen RGS13 fusion protein Ag3077
Vollständiger Name regulator of G-protein signaling 13
Berechnetes Molekulargewicht 159 aa, 19 kDa
Beobachtetes Molekulargewicht 17-19 kDa
GenBank-ZugangsnummerBC016667
Gene symbol RGS13
Gene ID (NCBI) 6003
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Regulator of G-protein signaling 13 (RGS13) is an R4 subfamily member that attenuates both Gαi and Gαq-dependent signaling including chemokine reponses in B cells (PMID: 11875076, PMID: 12193720). RGS13 interacted with both Gialpha and Gqalpha and strongly impaired signaling through G(i)-linked signaling pathways, including signaling through the chemokine receptors CXCR4 and CXCR5 (PMID: 12193720). Human mast cells express multiple RGS proteins, of which RGS13 is among the most abundant (PMID: 19017978).