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RGS9 Polyklonaler Antikörper

RGS9 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 17970-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of mouse brain tissue using RGS9 Polyclonal antibody (17970-1-AP)

    WB analysis of mouse brain using 17970-1-AP (same clone as 17970-1-PBS)

    mouse brain tissue were subjected to SDS PAGE followed by western blot with 17970-1-AP (RGS9 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17970-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of SH-SY5Y cells using RGS9 Polyclonal antibody (17970-1-AP)

    WB analysis of SH-SY5Y using 17970-1-AP (same clone as 17970-1-PBS)

    SH-SY5Y cells were subjected to SDS PAGE followed by western blot with 17970-1-AP (RGS9 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17970-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

17970-1-PBS bindet in WB, Indirect ELISA RGS9 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen RGS9 fusion protein Ag11976
Vollständiger Name regulator of G-protein signaling 9
Berechnetes Molekulargewicht 622 aa, 71 kDa
Beobachtetes Molekulargewicht 58 kDa, 70-75 kDa
GenBank-ZugangsnummerBC022504
Gene symbol RGS9
Gene ID (NCBI) 8787
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

RGS9 is a member of the RGS family of signaling proteins that suppress the activity of G proteins by promoting their deactivation. There are two splice isoforms of RGS9 with quite different properties and patterns of expression. RGS9-1 is mainly found in the eye and is involved in regulation of phototransduction in rod and cone cells of the retina, while RGS9-2 is is expressed specifically in the striatum, a brain region involved in controlling movement, motivation, mood and addition. This antibody got about 58kD in the mouse eye and 70kD in the mouse brain in western blotting, both in line with their expected masses. Defects in RGS9 are a cause of prolonged electroretinal response suppression (PERRS).