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RHBDL3 Polyklonaler Antikörper

RHBDL3 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 21671-1-PBS

Synonyme

EC:3.4.21.105, RHBDL4, Rhomboid related protein 3, Rhomboid-related protein 3, VRHO

Filter:
  • Western Blot (WB) analysis of various lysates using RHBDL3 Polyclonal antibody (21671-1-AP)

    WB analysis using 21671-1-AP (same clone as 21671-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 21671-1-AP (RHBDL3 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21671-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

21671-1-PBS bindet in WB, Indirect ELISA RHBDL3 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen RHBDL3 fusion protein Ag16499
Vollständiger Name rhomboid, veinlet-like 3 (Drosophila)
Berechnetes Molekulargewicht 404 aa, 45 kDa
Beobachtetes Molekulargewicht40 kDa
GenBank-ZugangsnummerBC100975
Gene symbol RHBDL3
Gene ID (NCBI) 162494
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

RHBDL3 (Rhomboid-related protein 3) is involved in a process known as regulated intramembrane proteolysis (RIP), where proteins are cleaved within the membrane to release functional polypeptides from their membrane anchors. It is expressed in several structures, including the central nervous system, embryo ectoderm, reproductive system, sensory organ, and thymus. RHBDL3 is also a prognostic marker in Glioblastoma multiforme, indicating its potential role in cancer-related pathways. It is expressed in various cell lines, particularly in those related to neuronal function and visual perception, with low cancer specificity.