RIM1 Polyklonaler Antikörper

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• KD/KO Validated

RIM1 Polyklonal Antikörper für WB, IHC, IP, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IP, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 24576-1-PBS

Synonyme

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  WB analysis using 24576-1-AP (same clone as 24576-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 24576-1-AP (RIM1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24576-1-PBS in a different storage buffer formulation.

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  IP experiment of mouse brain using 24576-1-AP (same clone as 24576-1-PBS)

  IP result of anti-RIM1 (IP:24576-1-AP, 4ug; Detection:24576-1-AP 1:1000) with mouse brain tissue lysate 4000ug. This data was developed using the same antibody clone with 24576-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 24576-1-AP (same clone as 24576-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 24576-1-AP (RIM1 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24576-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 24576-1-AP (same clone as 24576-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 24576-1-AP (RIM1 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24576-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

24576-1-PBS bindet in WB, IHC, IP, Indirect ELISA RIM1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: RIM1 fusion protein Ag20161
• Vollständiger Name: regulating synaptic membrane exocytosis 1
• Berechnetes Molekulargewicht: 1692 aa, 189 kDa
• Beobachtetes Molekulargewicht: 189 kDa
• GenBank-Zugangsnummer: BC152435
• Gene symbol: RIMS1
• Gene ID (NCBI): 22999
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

RIMS1 is a RAS gene superfamily member that regulates synaptic vesicle exocytosis. RIMS1 also plays a role in the regulation of voltage-gated calcium channels during neurotransmitter and insulin release. Mutations in RIMS1 have suggested a role cognition and have been identified as the cause of cone-rod dystrophy type 7.