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RIN2 Polyklonaler Antikörper

RIN2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31223-1-PBS

Synonyme

Ras and Rab interactor 2, Ras inhibitor JC265, RASSF4

Filter:
  • Western Blot (WB) analysis of various lysates using RIN2 Polyclonal antibody (31223-1-AP)

    WB analysis using 31223-1-AP (same clone as 31223-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31223-1-AP (RIN2 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31223-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

31223-1-PBS bindet in WB, Indirect ELISA RIN2 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen RIN2 fusion protein Ag35011
Vollständiger Name Ras and Rab interactor 2
Berechnetes Molekulargewicht100 kDa
Beobachtetes Molekulargewicht100-120 kDa
GenBank-ZugangsnummerNM_018993
Gene symbol RIN2
Gene ID (NCBI) 54453
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

RIN2 (Ras and Rab interactor 2), also known as RASSF4. RIN2 is mainly located in Golgi apparatus and participates in the process of material transport and secretion in cells. It is also distributed in cytoplasmic matrix, which may be related to signal transduction in cells. It is highly expressed in the brain, and also in the cerebellum, spinal cord and other nervous system tissues. RIN2 belongs to the family of Ras and Rab exchange factors and has a unique VPS9 domain. It can be used as a nucleotide exchange factor to activate the downstream small GTP enzymes Rab5 and R-Ras, thus starting intracellular signal transduction and regulating cytoskeleton recombination, synapse secretion and cell adhesion. The molecular weight of RIN2 is 100 kDa.