RIPK1 Rekombinanter Antikörper

RIPK1 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

251185E7

Kat-Nr. : 84036-6-PBS

Synonyme

EC:2.7.11.1, Receptor interacting serine/threonine protein kinase 1, Receptor-interacting protein 1, Receptor-interacting serine/threonine-protein kinase 1, RIP

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  WB analysis using 84036-6-RR (same clone as 84036-6-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84036-6-RR (RIPK1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84036-6-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

84036-6-PBS bindet in WB, Indirect ELISA RIPK1 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: RIPK1 fusion protein Ag31950
• Vollständiger Name: receptor (TNFRSF)-interacting serine-threonine kinase 1
• Berechnetes Molekulargewicht: 76KD
• Beobachtetes Molekulargewicht: 70-80 kDa
• GenBank-Zugangsnummer: NM_003804
• Gene symbol: RIPK1
• Gene ID (NCBI): 8737
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

RIPK1(Receptor-interacting serine/threonine-protein kinase 1) is primarily involved in mediating TNF-R1-induced cell activation, apoptosis, and necroptosis and belongs to a novel class of kinases that function in cell survival and cell death mechanisms(PMID:22685397 ). It has 2 isoforms produced by alternative splicing. It also can exist as a protein with a lower molecular weight of about 25 kDa and 45 kDa in HAEC and HUVEC(PMID:22685397).