RIPK2 Rekombinanter Antikörper

RIPK2 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250069D9

Kat-Nr. : 85760-4-PBS

Synonyme

CARD3, CARD-containing IL-1 beta ICE-kinase, CARD-containing interleukin-1 beta-converting enzyme-associated kinase, CARDIAK, CCK

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  WB analysis using 85760-4-RR (same clone as 85760-4-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 85760-4-RR (RIPK2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85760-4-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

85760-4-PBS bindet in WB, Indirect ELISA RIPK2 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: RIPK2 fusion protein Ag0909
• Vollständiger Name: receptor-interacting serine-threonine kinase 2
• Berechnetes Molekulargewicht: 61 kDa
• Beobachtetes Molekulargewicht: 46-55 kDa, 61-72 kDa
• GenBank-Zugangsnummer: BC004553
• Gene symbol: RIPK2
• Gene ID (NCBI): 8767
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

RIPK2 is also named as CARDIAK, RICK, RIP2 and belongs to the receptor-interacting serine/threonine-protein kinase(RIPK) family. RIPK2 functions as a key signaling protein in host defense responses induced by activation of the cytosolic pattern recognition receptors (PRR) NOD1 and NOD2. It has also been reported to mediate other cellular responses, including TLR signaling, caspase 1 activation , apoptosis and autophagy(PMID:22685397). It has 2 isoforms produced by alternative splicing.