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RNASEH2A Monoklonaler Antikörper

RNASEH2A Monoklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1A2E8

Kat-Nr. : 67976-1-PBS

Synonyme

AGS4, Aicardi-Goutieres syndrome 4 protein, EC:3.1.26.4, JUNB, Ribonuclease H2 subunit A

Filter:
  • Western Blot (WB) analysis of various lysates using RNASEH2A Monoclonal antibody (67976-1-Ig)

    WB analysis using 67976-1-Ig (same clone as 67976-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 67976-1-Ig (RNASEH2A antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67976-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human skin cancer tissue using RNASEH2A Monoclonal antibody (67976-1-Ig)

    IHC staining of human skin cancer using 67976-1-Ig (same clone as 67976-1-PBS)

    Immunohistochemical analysis of paraffin-embedded skin cancer slide using 67976-1-Ig (RNASEH2A antibody) at dilution of 1:1000 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67976-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

67976-1-PBS bindet in WB, IHC, Indirect ELISA RNASEH2A und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG2a
Klonalität Monoklonal
Typ Antikörper
Immunogen RNASEH2A fusion protein Ag9256
Vollständiger Name ribonuclease H2, subunit A
Berechnetes Molekulargewicht 299 aa, 33 kDa
Beobachtetes Molekulargewicht33 kDa
GenBank-ZugangsnummerBC011748
Gene symbol RNASEH2A
Gene ID (NCBI) 10535
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

RNASEH2A(Ribonuclease H2 subunit A) is also named as RNASEHI, RNHIA and belongs to the RNase HII family and Eukaryotic subfamily. It is involved in the removal of the initiator RNA primers of Okazaki fragments, an essential step during chromosomal DNA replication of the lagging strand(PMID:9482870). It is an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Defects in RNASEH2A are the cause of Aicardi-Goutieres syndrome type 4 (AGS4).