RND3 Monoklonaler Antikörper

• Featured Product
• KD/KO Validated

RND3 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

Hausschwein, human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

3H8F9

Kat-Nr. : 66228-1-PBS

Synonyme

ARHE, memB, Protein MemB, Rho family GTPase 3, Rho8, RhoE, RND3

---

• 

  WB analysis of fetal human brain using 66228-1-Ig (same clone as 66228-1-PBS)

  fetal human brain tissue were subjected to SDS PAGE followed by western blot with 66228-1-Ig (RND3 Antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66228-1-PBS in a different storage buffer formulation.

---

Geprüfte Anwendungen

Produktinformation

66228-1-PBS bindet in WB, Indirect ELISA RND3 und zeigt Reaktivität mit Hausschwein, human

• Getestete Reaktivität: Hausschwein, human
• Wirt / Isotyp: Maus / IgG2b
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: RND3 fusion protein Ag18839
• Vollständiger Name: Rho family GTPase 3
• Berechnetes Molekulargewicht: 244 aa, 27 kDa
• Beobachtetes Molekulargewicht: 29 kDa
• GenBank-Zugangsnummer: BC012513
• Gene symbol: RND3
• Gene ID (NCBI): 390
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Rnd3, also known as RhoE, belongs to the Rnd subclass of the Rho family of small guanosine triphosphate (GTP)-binding proteins. Rnd proteins are unique due to their inability to switch from a GTP-bound to GDP-bound conformation. The basic role of Rnd3 is to report as an endogenous antagonist of RhoA signaling-mediated actin cytoskeleton dynamics, which specifically contributes to cell migration and neuron polarity. Rnd3 also plays a critical role in arresting cell cycle distribution, inhibiting cell growth, and inducing apoptosis and differentiation.