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RNF126 Monoklonaler Antikörper

RNF126 Monoklonal Antikörper für WB, FC (Intra), ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IF, FC (Intra), ELISA

Konjugation

Unkonjugiert

Publikationen(7)

CloneNo.

1E1B10

Kat-Nr. : 66647-1-Ig

Synonyme

1E1B10, E3 ubiquitin-protein ligase RNF126, EC:2.3.2.27, RING finger protein 126



Geprüfte Anwendungen

Erfolgreiche Detektion in WBJurkat-Zellen, K-562-Zellen, Ramos-Zellen, RAW 264.7-Zellen
Erfolgreiche Detektion in FC (Intra)Jurkat-Zellen

Empfohlene Verdünnung

AnwendungVerdünnung
Western Blot (WB)WB : 1:1000-1:6000
Durchflusszytometrie (FC) (INTRA)FC (INTRA) : 0.25 ug per 10^6 cells in a 100 µl suspension
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

66647-1-Ig bindet in WB, IHC, IF, FC (Intra), ELISA RNF126 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
In Publikationen genannte Reaktivitäthuman
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen RNF126 fusion protein Ag13816
Vollständiger Name ring finger protein 126
Berechnetes Molekulargewicht 326 aa, 36 kDa
Beobachtetes Molekulargewicht 36-38 kDa
GenBank-ZugangsnummerBC001442
Gene symbol RNF126
Gene ID (NCBI) 55658
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS with 0.02% sodium azide and 50% glycerol
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

RNF126, also named as E3 ubiquitin-protein ligase RNF126, is a 326 amino acid protein, which is highly expressed in liver and testis. RNF126 (RING finger protein 126) contains one RING-type zinc finger domain and is known to interact with TRAF6 (a ubiquitin ligase) and BAT3 (an apoptotic regulator).

Protokolle

PRODUKTSPEZIFISCHE PROTOKOLLE
WB protocol for RNF126 antibody 66647-1-IgProtokoll herunterladen
STANDARD-PROTOKOLLE
Klicken Sie hier, um unsere Standardprotokolle anzuzeigen

Publikationen

SpeciesApplicationTitle
humanWB

Mol Cell

RNF126-Mediated Reubiquitination Is Required for Proteasomal Degradation of p97-Extracted Membrane Proteins.

Authors - Xianyan Hu
  • KD Validated
humanWB

Exp Eye Res

Retinitis pigmentosa 2 pathogenic mutants degrade through BAG6/HUWE1 complex.

Authors - Jing Zhang
humanWB

Cell Death Dis

ARIH2 regulates the proliferation, DNA damage and chemosensitivity of gastric cancer cells by reducing the stability of p21 via ubiquitination.

Authors - Shengjun Geng
humanWB

Cell Chem Biol

Bortezomib inhibits ZIKV/DENV by interfering with viral polyprotein cleavage via the ERAD pathway

Authors - Yali Ci
humanIHC,IF

J Cell Physiol

ZNF263 cooperates with ZNF31 to promote the drug resistance and EMT of pancreatic cancer through transactivating RNF126

Authors - Jiawei Zhang
humanWB

ACS Cent Sci

DCAF16-Based Covalent Handle for the Rational Design of Monovalent Degraders

Authors - Melissa Lim
  • KO Validated