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RNF135 Rekombinanter Antikörper

RNF135 Rekombinant Antikörper für IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Ratte

Anwendung

IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241606D8

Kat-Nr. : 84984-1-PBS

Synonyme

RIG I E3 ubiquitin ligase, REUL, L13, EC:2.3.2.27, E3 ubiquitin-protein ligase RNF135

Filter:
  • Immunofluorescence (IF) / fluorescent staining of PC-12 cells using RNF135 Recombinant antibody (84984-1-RR)

    IF Staining of PC-12 using 84984-1-RR (same clone as 84984-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed PC-12 cells using RNF135 antibody (84984-1-RR, Clone: 241606D8 ) at dilution of 1:250 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84984-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84984-1-RR

    Affinity and Kinetic Characterization of 84984-1-RR

    Biolayer interferometry (BLl) kinetic assays of 84984-1-RR against Human RNF135 were performed. The affinity constant is 49.1 nM.

Geprüfte Anwendungen

Produktinformation

84984-1-PBS bindet in IF/ICC, Indirect ELISA RNF135 und zeigt Reaktivität mit human, Ratten

Getestete Reaktivität human, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen RNF135 fusion protein Ag18821
Vollständiger Name ring finger protein 135
Berechnetes Molekulargewicht 432 aa, 48 kDa
Beobachtetes Molekulargewicht 48 kDa
GenBank-ZugangsnummerBC005084
Gene symbol RNF135
Gene ID (NCBI) 84282
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Ring finger protein 135 (RNF135), located on chromosome 17q11.2, is a RING finger domain-containing E3 ubiquitin ligase that was identified as a bio-marker and therapy target of glioblastoma (PMID: 26856755). RNF135 facilitates RIG-I C-terminal ubiquitination to up-regulate RIG-I-mediated IFN signaling and suppress viral replication.