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RPL13 Rekombinanter Antikörper

RPL13 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

250752B10

Kat-Nr. : 86205-1-PBS

Synonyme

60S ribosomal protein L13, BBC1, D16S444E, Large ribosomal subunit protein eL13, OK/SW-cl.46

Filter:
  • Western Blot (WB) analysis of various lysates using RPL13 Recombinant monoclonal antibody (86205-1-RR)

    WB analysis using 86205-1-RR (same clone as 86205-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 86205-1-RR (RPL13 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86205-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 86205-1-RR

    Affinity and Kinetic Characterization of 86205-1-RR

    Biolayer interferometry (BLl) kinetic assays of 86205-1-RR against Human RPL13 were performed. The affinity constant is 0.991 nM.

Geprüfte Anwendungen

Produktinformation

86205-1-PBS bindet in WB, Indirect ELISA RPL13 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen RPL13 fusion protein Ag1814
Vollständiger Name ribosomal protein L13
Berechnetes Molekulargewicht 24 kDa
Beobachtetes Molekulargewicht 24 kDa
GenBank-ZugangsnummerBC014167
Gene symbol RPL13
Gene ID (NCBI) 6137
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The mammalian ribosome comprises 79 ribosomal proteins and four rRNAs, which combine in equimolar ratios to form the small (40S) and large (60S) subunits. Ribosome proteins are a direct and critical target of the PI3K pathway in promoting growth.[PMID:15289434]. RPL13 may be a plausible candidate tumor suppressor gene, as knocking down L13 expression using small interfering RNA (siRNA) resulted in drastic attenuation of cancer cell growth with significant G1 and G2/M arrest of the cell cycle[PMID:16786168].