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RRAD Polyklonaler Antikörper

RRAD Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 27763-1-PBS

Synonyme

Ras associated with diabetes, RAD1, RAD, GTP-binding protein RAD, GTP binding protein RAD

Filter:
  • Western Blot (WB) analysis of various lysates using RRAD Polyclonal antibody (27763-1-AP)

    WB analysis using 27763-1-AP (same clone as 27763-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 27763-1-AP (RRAD antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27763-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of SKOV-3 cells using RRAD Polyclonal antibody (27763-1-AP)

    WB analysis of SKOV-3 using 27763-1-AP (same clone as 27763-1-PBS)

    WB result of RRAD antibody (27763-1-AP; 1:5000; incubated at room temperature for 1.5 hours) with sh-Control and sh-RRAD transfected SKOV-3 cells. This data was developed using the same antibody clone with 27763-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

27763-1-PBS bindet in WB, Indirect ELISA RRAD und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen RRAD fusion protein Ag26869
Vollständiger Name Ras-related associated with diabetes
Berechnetes Molekulargewicht 33 kDa
Beobachtetes Molekulargewicht 29-34 kDa
GenBank-ZugangsnummerBC057815
Gene symbol RRAD
Gene ID (NCBI) 6236
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

RRAD is also named as RAD1. RRAD, a member of the Ras-like small GTPase family, was initially identified as a gene associated with Type II diabetes since it was found to be overexpressed in some Type II diabetic patients (PMID: 8248782). RRAD overexpression reduced insulin-stimulated glucose uptake in cultured muscle and adipocytes cells (PMID: 8798502). RRAD was found to be frequently down-regulated in different types of human cancers, including lung cancer, breast cancer, and nasopharyngeal carcinoma, etc, due to the hypermethylation of its promoter (PMID: 17195088).