RTN2 Polyklonaler Antikörper

• Featured Product
• KD/KO Validated

RTN2 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 11168-1-PBS

Synonyme

---

• 

  WB analysis of mouse skeletal muscle using 11168-1-AP (same clone as 11168-1-PBS)

  mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 11168-1-AP (RTN2 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11168-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human skeletal muscle using 11168-1-AP (same clone as 11168-1-PBS)

  human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 11168-1-AP (RTN2 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11168-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse skeletal muscle using 11168-1-AP (same clone as 11168-1-PBS)

  mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 11168-1-AP (RTN2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11168-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse skeletal muscle using 11168-1-AP (same clone as 11168-1-PBS)

  mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 11168-1-AP (RTN2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11168-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human skeletal muscle using 11168-1-AP (same clone as 11168-1-PBS)

  human skeletal muscle tissue were subjected to SDS PAGE followed by western blot with 11168-1-AP (RTN2 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11168-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skeletal muscle using 11168-1-AP (same clone as 11168-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skeletal muscle slide using 11168-1-AP (RTN2 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 11168-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human skeletal muscle using 11168-1-AP (same clone as 11168-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human skeletal muscle slide using 11168-1-AP (RTN2 Antibody) at dilution of 1:50. This data was developed using the same antibody clone with 11168-1-PBS in a different storage buffer formulation.

---

Geprüfte Anwendungen

Produktinformation

11168-1-PBS bindet in WB, IHC, Indirect ELISA RTN2 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: RTN2 fusion protein Ag1655
• Vollständiger Name: reticulon 2
• Berechnetes Molekulargewicht: 59 kDa, 51 kDa, 22 kDa
• Beobachtetes Molekulargewicht: 20-23 kDa
• GenBank-Zugangsnummer: BC014244
• Gene symbol: RTN2
• Gene ID (NCBI): 6253
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Reticulon (RTN) proteins are a group of membrane-bound proteins that largely reside in endoplasmic reticulum (ER) (PMID: 18177508). Reticulon proteins share a common sequence feature, the reticulon homology domain (RHD). They are involved in shaping the tubular endoplasmic reticulum network, membrane trafficking, inhibition of axonal growth, and apoptosis (PMID: 24218324). Four mammalian reticulons (RTN1-4) exist. Human RTN2 gene produces three isoforms termed RTN2-A, RTN2-B, and RTN2-C. Isoform RTN2-C has a calculated molecular weight of 22 kDa and is highly expressed in skeletal muscle.