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RTTN Polyklonaler Antikörper

RTTN Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31232-1-PBS

Synonyme

Rotatin, MSSP

Filter:
  • Western Blot (WB) analysis of various lysates using RTTN Polyclonal antibody (31232-1-AP)

    WB analysis using 31232-1-AP (same clone as 31232-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31232-1-AP (RTTN antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31232-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

31232-1-PBS bindet in WB, Indirect ELISA RTTN und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen RTTN fusion protein Ag34960
Vollständiger Name rotatin
Berechnetes Molekulargewicht249 kDa
Beobachtetes Molekulargewicht246 kDa
GenBank-ZugangsnummerNM_173630
Gene symbol RTTN
Gene ID (NCBI) 25914
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

RTTN, also known as Rotatin, is an evolutionarily conserved protein that is associated with the centrosome and plays a crucial role in centriole biogenesis. It is found in many organisms and was initially identified in a mutant mouse that exhibited defects in axial rotation and left-right specification. RTTN is required for proper mitotic progression, the maintenance of spindle pole integrity, and correct spindle positioning. Loss of RTTN can lead to mitotic defects, including G2/M phase arrest and increased aneuploidy cells.