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RUNX2 Rekombinanter Antikörper

RUNX2 Rekombinant Antikörper für WB, IP, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IP, ELISA

Konjugation

Unkonjugiert

CloneNo.

1G5

Kat-Nr. : 82636-2-PBS

Synonyme

AML3, CBF alpha 1, CBFA1, CCD, CCD1, Oncogene AML 3, OSF 2, OSF2, PEA2 alpha A, PEA2aA, PEBP2 alpha A, PEBP2A, PEBP2A1, PEBP2A2, PEBP2aA, PEBP2aA1, RUNX2

Filter:
  • Western Blot (WB) analysis of various lysates using RUNX2 Recombinant antibody (82636-2-RR)

    WB analysis using 82636-2-RR (same clone as 82636-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82636-2-RR (RUNX2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82636-2-PBS in a different storage buffer formulation.

  • Immunoprecipitation (IP) experiment of ROS1728 cells using RUNX2 Recombinant antibody (82636-2-RR)

    IP experiment of ROS1728 using 82636-2-RR (same clone as 82636-2-PBS)

    IP result of anti-RUNX2 (IP:82636-2-RR, 4ug; Detection:82636-2-RR 1:500) with ROS1728 cells lysate 2080 ug. This data was developed using the same antibody clone with 82636-2-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

82636-2-PBS bindet in WB, IP, ELISA RUNX2 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Peptid
Vollständiger Name runt-related transcription factor 2
Berechnetes Molekulargewicht 57 kDa
Beobachtetes Molekulargewicht57-60 kDa
GenBank-ZugangsnummerNM_004348
Gene symbol RUNX2
Gene ID (NCBI) 860
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

RUNX2, also named as AML3, CBFA1, OSF2 and PEBP2A, is a Transcription factor which involved in osteoblastic differentiation and skeletal morphogenesis. It is essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters By similarity. RUNX2 inhibits MYST4-dependent transcriptional activation.