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S1PR2 Polyklonaler Antikörper
S1PR2 Polyklonal Antikörper für WB, IF-P, IF-Fro, ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human und mehr (2)
Anwendung
WB, IHC, IF-P, IF-Fro, IP, ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 21180-1-AP
Synonyme
Geprüfte Anwendungen
| Erfolgreiche Detektion in WB | HeLa-Zellen, HuH-7-Zellen, MCF-7-Zellen, MDA-MB-231-Zellen |
| Erfolgreiche Detektion in IF-P | Maushirngewebe |
| Erfolgreiche Detektion in IF-Fro | Maushirngewebe |
Empfohlene Verdünnung
| Anwendung | Verdünnung |
|---|---|
| Western Blot (WB) | WB : 1:500-1:3000 |
| Immunfluoreszenz (IF)-P | IF-P : 1:200-1:800 |
| Immunfluoreszenz (IF)-FRO | IF-FRO : 1:50-1:500 |
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Veröffentlichte Anwendungen
| KD/KO | See 8 publications below |
| WB | See 48 publications below |
| IHC | See 10 publications below |
| IF | See 13 publications below |
| IP | See 2 publications below |
Produktinformation
21180-1-AP bindet in WB, IHC, IF-P, IF-Fro, IP, ELISA S1PR2 und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| In Publikationen genannte Reaktivität | human, Maus, Ratte |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Polyklonal |
| Typ | Antikörper |
| Immunogen | S1PR2 fusion protein Ag15470 |
| Vollständiger Name | sphingosine-1-phosphate receptor 2 |
| Berechnetes Molekulargewicht | 353 aa, 39 kDa |
| Beobachtetes Molekulargewicht | 40-50 kDa |
| GenBank-Zugangsnummer | BC069598 |
| Gene symbol | S1PR2 |
| Gene ID (NCBI) | 9294 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Antigen-Affinitätsreinigung |
| Lagerungspuffer | PBS with 0.02% sodium azide and 50% glycerol |
| Lagerungsbedingungen | Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
S1PR2 (sphingosine-1-phosphate receptor 2), also known as S1P2 or EDG5, is one of five G-protein-coupled receptors for sphingosine-1-phosphate (S1P), a biologically active metabolic product of sphingolipid (PMID: 18787560). S1P and its receptors have important regulatory functions in normal physiology and disease processes, particularly involving the immune, central nervous, and cardiovascular systems (PMID: 21339489). S1PR2 plays a role in acute vascular inflammation (PMID: 23723450). S1PR2 signaling is implicated in STAT3 activation (PMID: 22606352).
Protokolle
| PRODUKTSPEZIFISCHE PROTOKOLLE | |
|---|---|
| WB protocol for S1PR2 antibody 21180-1-AP | Protokoll herunterladen |
| IF protocol for S1PR2 antibody 21180-1-AP | Protokoll herunterladen |
| STANDARD-PROTOKOLLE | |
|---|---|
| Klicken Sie hier, um unsere Standardprotokolle anzuzeigen |
Publikationen
| Species | Application | Title |
|---|---|---|
Gastroenterology Pancreatic acinar cells-derived sphingosine-1-phosphate contributes to fibrosis of chronic pancreatitis via inducing autophagy and activation of pancreatic stellate cells | ||
Nat Commun Critical role of sphingosine-1-phosphate receptor-2 in the disruption of cerebrovascular integrity in experimental stroke.
| ||
EMBO Mol Med Therapeutic development of group B Streptococcus meningitis by targeting a host cell signaling network involving EGFR.
| ||
Theranostics Endothelial S1pr2 regulates post-ischemic angiogenesis via AKT/eNOS signaling pathway.
| ||
Rezensionen
The reviews below have been submitted by verified Proteintech customers who received an incentive for providing their feedback.
FH Edma (Verified Customer) (03-03-2025) | The antibody quite nice in western blot, but I have to test it in other cell types
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