S1PR2 Polyklonaler Antikörper

• Featured Product
• KD/KO Validated

S1PR2 Polyklonal Antikörper für IF-P

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

IF-P

Konjugation

CoraLite®594 Fluorescent Dye

Kat-Nr. : CL594-21180

Synonyme

AGR16, EDG 5, EDG5, Gpcr13, H218, LPB2, S1P receptor 2, S1P receptor Edg 5, S1P2, S1PR2

---

• 

  IF Staining of mouse brain using CL594-21180

  Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using CoraLite®594 S1PR2 antibody (CL594-21180) at dilution of 1:200.

• 

  IF Staining of mouse brain using CL594-21180

  Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using CoraLite®594 S1PR2 antibody (CL594-21180) at dilution of 1:200.

---

Geprüfte Anwendungen

• Erfolgreiche Detektion in IF-P: Maushirngewebe

Empfohlene Verdünnung

• Immunfluoreszenz (IF)-P: IF-P : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

CL594-21180 bindet in IF-P S1PR2 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: S1PR2 fusion protein Ag15470
• Vollständiger Name: sphingosine-1-phosphate receptor 2
• Berechnetes Molekulargewicht: 353 aa, 39 kDa
• Beobachtetes Molekulargewicht: 40-50 kDa
• GenBank-Zugangsnummer: BC069598
• Gene symbol: S1PR2
• Gene ID (NCBI): 9294
• Konjugation: CoraLite®594 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 588 nm / 604 nm
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA
• Lagerungsbedingungen: Bei -20°C lagern. Vor Licht schützen. Nach dem Versand ein Jahr stabil. Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

S1PR2 (sphingosine-1-phosphate receptor 2), also known as as S1P2 or EDG5, is one of five G-protein-coupled receptors for sphingosine-1-phosphate (S1P), a biologically active metabolic product of sphingolipid (PMID: 18787560). S1P and its receptors have important regulatory functions in normal physiology and disease processes, particularly involving the immune, central nervous, and cardiovascular systems (PMID: 21339489). S1PR2 plays a role in acute vascular inflammation (PMID: 23723450). S1PR2 signaling is implicated in STAT3 activation (PMID: 22606352).