SAA Polyklonaler Antikörper

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• KD/KO Validated

SAA Polyklonal Antikörper für IHC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, ELISA

Konjugation

Unkonjugiert

Publikationen(3)

Kat-Nr. : 16721-1-AP

Synonyme

SAA1, serum amyloid A1, Serum amyloid A-1 protein, Serum amyloid protein A(2-102), Serum amyloid protein A(2-103)

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  IHC staining of human liver using 16721-1-AP

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 16721-1-AP (SAA1 antibody) at dilution of 1:100 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of human liver cancer using 16721-1-AP

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 16721-1-AP (SAA1 antibody) at dilution of 1:100 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of human liver cancer using 16721-1-AP

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 16721-1-AP (SAA1 antibody) at dilution of 1:100 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of human small intestine using 16721-1-AP

  Immunohistochemical analysis of paraffin-embedded human small intestine tissue slide using 16721-1-AP (SAA1 antibody) at dilution of 1:100 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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Geprüfte Anwendungen

• Erfolgreiche Detektion in IHC: humanes Leberkarzinomgewebe, humanes Lebergewebe, humanes Dünndarmgewebe; Hinweis: Antigendemaskierung mit TE-Puffer pH 9,0 empfohlen. (*) Wahlweise kann die Antigendemaskierung auch mit Citratpuffer pH 6,0 erfolgen.

Empfohlene Verdünnung

• Immunhistochemie (IHC): IHC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• KD/KO: See 1 publications below
• WB: See 1 publications below
• IHC: See 3 publications below

Produktinformation

16721-1-AP bindet in WB, IHC, ELISA SAA und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• In Publikationen genannte Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: SAA fusion protein Ag10160
• Vollständiger Name: serum amyloid A1
• Berechnetes Molekulargewicht: 122 aa, 14 kDa
• GenBank-Zugangsnummer: BC105796
• Gene symbol: SAA1
• Gene ID (NCBI): 6288
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Serum amyloid A1(SAA1) is a member of the serum amyloid A family of apolipoproteins. SAA1 is an acute phase apolipoprotein reactant produced mainly by hepatocytes and under regulation of inflammatory cytokines. Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA1 protein. Elevated serum SAA1 protein levels may be associated with lung cancer(PMID: 1463770). This antibody can recognize SAA1 and SAA2.

Publikationen

Species	Application	Title
human	WB,IHC	Mol Oncol; Serum amyloid A1 in combination with integrin αVβ3 increases glioblastoma cells mobility and progression.; Authors - Ching-Yu Lin ; KD Validated
human	IHC	J Transl Med; Plasma proteomic analysis of autoimmune hepatitis in an improved AIH mouse model.; Authors - Han Wang
human	IHC	Nat Commun; Multi-omics with dynamic network biomarker algorithm prefigures organ-specific metastasis of lung adenocarcinoma; Authors - Xiaoshen Zhang