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SALL4 Monoklonaler Antikörper

SALL4 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2B5B2

Kat-Nr. : 66236-1-PBS

Synonyme

2B5B2, DRRS, HSAL4, Sal like protein 4, Sal-like protein 4

Filter:
  • Western Blot (WB) analysis of K-562 cells using SALL4 Monoclonal antibody (66236-1-Ig)

    WB analysis of K-562 using 66236-1-Ig (same clone as 66236-1-PBS)

    K-562 cells were subjected to SDS PAGE followed by western blot with 66236-1-Ig (SALL4 Antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66236-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of K-562 cells using SALL4 Monoclonal antibody (66236-1-Ig)

    WB analysis of K-562 using 66236-1-Ig (same clone as 66236-1-PBS)

    K-562 cells were subjected to SDS PAGE followed by western blot with 66236-1-Ig (SALL4 Antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 66236-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

66236-1-PBS bindet in WB, Indirect ELISA SALL4 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen SALL4 fusion protein Ag17480
Vollständiger Name sal-like 4 (Drosophila)
Berechnetes Molekulargewicht 1053 aa, 112 kDa
Beobachtetes Molekulargewicht 165 kDa
GenBank-ZugangsnummerBC111714
Gene symbol SALL4
Gene ID (NCBI) 57167
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SALL4, also named as Sal-like protein 4 or Zinc finger protein 797, Contains 7 C2H2-type zinc fingers and belongs to the sal C2H2-type zinc-finger protein family. SALL4 is constitutively expressed in acute myeloid leukemia. The constitutive expression of SALL4in mice is sufficient to induce MDS-like symptoms and transformation to AML that is transplantable. SALL4 is able to bind beta-catenin and activate the Wnt/beta-catenin signaling pathway. Sequence analysis of the larger cDNA fragment isolated revealed a single, large open-reading frame, designated as SALL4A, that started from a strong consensus initiation sequence and was expected to encode 1053 amino acids. The other splicing variant of SALL4, designated SALL4B, lacked the region corresponding to amino acids 385 to 820 of the full-length SALL4A. The putative protein encoded by SALL4B cDNA was expected to consist of 617 amino acids.