SC4MOL Rekombinanter Antikörper

SC4MOL Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

241988B11

Kat-Nr. : 84742-1-RR

Synonyme

ERG25, DESP4, 241988B11

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  WB analysis using 84742-1-RR

  mouse adipose tissue were subjected to SDS PAGE followed by western blot with 84742-1-RR (SC4MOL antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

• 

  Affinity and Kinetic Characterization of 84742-1-RR

  Biolayer interferometry (BLl) kinetic assays of 84742-1-RR against Human SC4MOL were performed. The affinity constant is 12.3 nM.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Maus-Fettgewebe, Mauslebergewebe, Maus-Dünndarmgewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

84742-1-RR bindet in WB, ELISA SC4MOL und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: SC4MOL fusion protein Ag34758
• Vollständiger Name: sterol-C4-methyl oxidase-like
• Beobachtetes Molekulargewicht: 36 kDa
• GenBank-Zugangsnummer: BC107879
• Gene symbol: SC4MOL
• Gene ID (NCBI): 6307
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SC4MOL(sterol C4-methyl oxidase-like), an intermediate enzyme in the cholesterol biosynthetic pathway, was included in the library based on its representation in a high confidence GEO transcriptional profiling dataset as a transcript that rapidly undergoes significant expression change in response to stimulation or inhibition of EGFR. Among the validated hits that increased cell killing by common EGFR antagonists, SC4MOL was consistently one of the most effective modulators. (PMID: 23125191)