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SCARA5 Polyklonaler Antikörper

SCARA5 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 55390-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of mouse liver tissue using SCARA5 Polyclonal antibody (55390-1-AP)

    WB analysis of mouse liver using 55390-1-AP (same clone as 55390-1-PBS)

    mouse liver tissue were subjected to SDS PAGE followed by western blot with 55390-1-AP (SCARA5 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 55390-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

55390-1-PBS bindet in WB, Indirect ELISA SCARA5 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name scavenger receptor class A, member 5 (putative)
Berechnetes Molekulargewicht 54 kDa
Beobachtetes Molekulargewicht 43 kDa
GenBank-ZugangsnummerNM_173833
Gene symbol SCARA5
Gene ID (NCBI) 286133
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SCARA5 belongs to the SCARA5 family. It is a ferritin receptor that mediates non-transferrin-dependent delivery of iron. SCARA5 mediates cellular uptake of ferritin-bound iron by stimulating ferritin endocytosis from the cell surface with consequent iron delivery within the cell. Delivery of iron to cells by ferritin is required for the development of specific cell types, suggesting the existence of cell type-specific mechanisms of iron traffic in organogenesis, which alternatively utilize transferrin or non-transferrin iron delivery pathways. Ferritin mediates iron uptake in capsule cells of the developing kidney. SCARA5 binds preferrentially ferritin light chain (FTL) compared to heavy chain (FTH1). This antibody can recognize isoform 1,2 and 3 of SCARA5.