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SCARF1 Polyklonaler Antikörper

SCARF1 Polyklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 28174-1-PBS

Synonyme

Acetyl LDL receptor, KIAA0149, Scavenger receptor class F member 1, Scavenger receptor expressed by endothelial cells 1, SREC

Filter:
  • Western Blot (WB) analysis of various lysates using SCARF1 Polyclonal antibody (28174-1-AP)

    WB analysis using 28174-1-AP (same clone as 28174-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 28174-1-AP (SCARF1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28174-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HepG2 cells using SCARF1 Polyclonal antibody (28174-1-AP)

    IF Staining of HepG2 using 28174-1-AP (same clone as 28174-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed HepG2 cells using SCARF1 antibody (28174-1-AP) at dilution of 1:400 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), CL594-phalloidin (red). This data was developed using the same antibody clone with 28174-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

28174-1-PBS bindet in WB, IF/ICC, Indirect ELISA SCARF1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SCARF1 fusion protein Ag28079
Vollständiger Name scavenger receptor class F, member 1
Berechnetes Molekulargewicht 830 aa, 87 kDa
Beobachtetes Molekulargewicht90 kDa, 180 kDa
GenBank-ZugangsnummerBC039735
Gene symbol SCARF1
Gene ID (NCBI) 8578
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Scavenger receptor class F member 1 (SCARF1), also known as scavenger receptor expressed by endothelial cells (SREC)-I, belongs to the scavenger receptor (SR) superfamily. SCARF1 has been shown to bind modified low density lipoproteins (LDLs), including acetylated (Ac-) and oxidized (ox-) LDLs (PMID: 29725698; PMID: 15145948). In addition to binding and internalizing a diverse range of endogenous proteins, SCARF1 also binds a wide array of viral, fungal, and bacterial antigens (PMID: 29242513). SCARF1 has a calculated molecular weight of 87 kDa, with a molecular weight of 140-160 kDa due to N-glycosylation (PMID: 22279061; PMID: 15145948). SCARF1 can also exist as a dimer (~ 180 kDa) and a truncated soluble form (~ 60 kDa) (PMID: 29242513; PMID: 29725698).