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SCN1A Polyklonaler Antikörper

SCN1A Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 28079-1-PBS

Synonyme

sodium channel, Pan, FEB3, GEFSP2, HBSCI, NAC1

Filter:
  • Western Blot (WB) analysis of PC-12 cells using SCN1A Polyclonal antibody (28079-1-AP)

    WB analysis of PC-12 using 28079-1-AP (same clone as 28079-1-PBS)

    PC-12 cells were subjected to SDS PAGE followed by western blot with 28079-1-AP (SCN1A antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28079-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using SCN1A Polyclonal antibody (28079-1-AP)

    WB analysis using 28079-1-AP (same clone as 28079-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 28079-1-AP (SCN1A antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28079-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

28079-1-PBS bindet in WB, Indirect ELISA SCN1A und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SCN1A fusion protein Ag25942
Vollständiger Name sodium channel, voltage-gated, type I, alpha subunit
Berechnetes Molekulargewicht 229 kDa
Beobachtetes Molekulargewicht 229-240 kDa
GenBank-ZugangsnummerNM_001165963
Gene symbol SCN1A
Gene ID (NCBI) 6323
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Sodium channel protein type 1 subunit alpha (SCN1A) is a multi-pass membrane protein that is crucial for generating and transmitting electrical signals in neurons, thereby contributing to the sensory perception of mechanically-induced pain (PMID: 14672992). SCN1A also regulates neuronal excitability and is essential for normal brain function (PMID: 37139072; 20831750).