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SCN2A Polyklonaler Antikörper

SCN2A Polyklonal Antikörper für WB, IF-P, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IF-P, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 27551-1-PBS

Synonyme

BFIC3, HBA, HBSC II, HBSCI, HBSCII

Filter:
  • Western Blot (WB) analysis of various lysates using SCN2A Polyclonal antibody (27551-1-AP)

    WB analysis using 27551-1-AP (same clone as 27551-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 27551-1-AP (SCN2A antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27551-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using SCN2A Polyclonal antibody (27551-1-AP)

    WB analysis using 27551-1-AP (same clone as 27551-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 27551-1-AP (SCN2A antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 27551-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of mouse brain tissue using SCN2A Polyclonal antibody (27551-1-AP)

    IF Staining of mouse brain using 27551-1-AP (same clone as 27551-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using SCN2A antibody (27551-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 27551-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

27551-1-PBS bindet in WB, IF-P, Indirect ELISA SCN2A und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SCN2A fusion protein Ag26022
Vollständiger Name sodium channel, voltage-gated, type II, alpha subunit
Berechnetes Molekulargewicht 228 kDa
Beobachtetes Molekulargewicht~250 kDa
GenBank-ZugangsnummerNM_001040142
Gene symbol SCN2A
Gene ID (NCBI) 6326
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The Sodium Channel, Voltage-Gated, Type II, Alpha (SCN2A) gene encodes the neuronal sodium channel NaV1.2. There are two major developmentally regulated splice isoforms of NaV1.2 that use mutually exclusive copies of the fifth coding exon and differ by one amino acid at position 209: Asparagine (Asn/N) vs. Aspartic acid (Asp/D). NaV1.2 is one of several sodium channels involved in initiation and propagation of action potentials in neurons. It's widely expressed throughout the human central nervous system, but not in peripheral tissues. (PMID: 29691040)