SCN3B Rekombinanter Antikörper

SCN3B Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

230316F8

Kat-Nr. : 82959-1-RR

Synonyme

Sodium channel subunit beta 3, Sodium channel regulatory subunit beta-3, SCNB3, KIAA1158, HSA243396

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  WB analysis using 82959-1-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 82959-1-RR (SCN3B antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours.

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  Affinity and Kinetic Characterization of 82959-1-RR

  Biolayer interferometry (BLl) kinetic assays of 82959-1-RR against Human SCN3B were performed. The affinity constant is 0.429 nM.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: HEK-293-Zellen, fetales humanes Hirngewebe, Maushirngewebe, Rattenhirngewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:2000-1:10000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

82959-1-RR bindet in WB, ELISA SCN3B und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: SCN3B fusion protein Ag23201
• Vollständiger Name: sodium channel, voltage-gated, type III, beta
• Beobachtetes Molekulargewicht: 29 kDa
• GenBank-Zugangsnummer: BC126265
• Gene symbol: SCN3B
• Gene ID (NCBI): 55800
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The sodium voltage-gated channel beta subunit 3 (SCN3B) plays a crucial role in electrically excitable cells and conduction tissue in the heart. Some previous studies have established that genetic modification in sodium voltage-channel genes encoding for the cardiac β-subunits, such as SCN1B, SCN2B, SCN3B and SCN4B, can result in atrial fibrillation (AF). (PMID: 36362949)