SCP2 Polyklonaler Antikörper
SCP2 Polyklonal Antikörper für ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Maus, Ratte
Anwendung
WB, ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 19182-1-AP
Synonyme
Geprüfte Anwendungen
Veröffentlichte Anwendungen
WB | See 4 publications below |
Produktinformation
19182-1-AP bindet in WB, ELISA SCP2 und zeigt Reaktivität mit human, Maus, Ratten
Getestete Reaktivität | human, Maus, Ratte |
In Publikationen genannte Reaktivität | Ratte |
Wirt / Isotyp | Kaninchen / IgG |
Klonalität | Polyklonal |
Typ | Antikörper |
Immunogen | SCP2 fusion protein Ag6002 |
Vollständiger Name | sterol carrier protein 2 |
Berechnetes Molekulargewicht | 59 kDa |
Beobachtetes Molekulargewicht | 46 kDa, 58 kDa |
GenBank-Zugangsnummer | BC067108 |
Gene symbol | SCP2 |
Gene ID (NCBI) | 6342 |
Konjugation | Unkonjugiert |
Form | Liquid |
Reinigungsmethode | Antigen-Affinitätsreinigung |
Lagerungspuffer | PBS with 0.02% sodium azide and 50% glycerol |
Lagerungsbedingungen | Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
SCP2 (Sterol carrier protein-2), also called nonspecific lipid-transfer protein, is thought to play a major role in intracellular lipid transport and metabolism. Mutations of SCP2 have been associated with diseases involving abnormalities in lipid trafficking, such as Zellweger syndrome. The alternative splicing generates 58 kDa SCPx and 13-15 kDa SCP2 proteins, both of which contain a C-terninal SCP2 domain. In addition to the SCP2 domain, SCPx also contains an amino-terminal thiolase domain. The proteolytic cleavage of SCPx occurred when it was imported into peroxisomes, giving rise to a 44-46 kDa thiolase and a 13-15 kDa SCP2. 19182-1-AP antibody recognizes the intact 58 kDa SCPx protein as well as 44-46 kDa thiolase.
Protokolle
PRODUKTSPEZIFISCHE PROTOKOLLE | |
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WB protocol for SCP2 antibody 19182-1-AP | Protokoll herunterladen |
STANDARD-PROTOKOLLE | |
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Klicken Sie hier, um unsere Standardprotokolle anzuzeigen |
Publikationen
Species | Application | Title |
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J Biol Chem A Cargo-centered Perspective on the PEX5 Receptor-mediated Peroxisomal Protein Import Pathway. | ||
FEBS J Membrane topologies of PEX13 and PEX14 provide new insights on the mechanism of protein import into peroxisomes. | ||
J Biol Chem The peroxisomal matrix protein translocon is a large cavity-forming protein assembly into which PEX5 protein enters to release its cargo. | ||
Methods Mol Biol Determining the Topology of Peroxisomal Proteins Using Protease Protection Assays. |