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SCRT1 Polyklonaler Antikörper

SCRT1 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31577-1-PBS

Synonyme

SCRT, Scratch 1, hScrt

Filter:
  • Western Blot (WB) analysis of various lysates using SCRT1 Polyclonal antibody (31577-1-AP)

    WB analysis using 31577-1-AP (same clone as 31577-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31577-1-AP (SCRT1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31577-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

31577-1-PBS bindet in WB, Indirect ELISA SCRT1 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SCRT1 fusion protein Ag36215
Vollständiger Name scratch homolog 1, zinc finger protein (Drosophila)
Beobachtetes Molekulargewicht36 kDa
GenBank-ZugangsnummerBC168377
Gene symbol SCRT1
Gene ID (NCBI) 83482
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SCRT1 (Transcriptional repressor scratch 1), which is expressed in many tissues, especially in brain and adrenal gland. In addition, SCRT1 is also expressed in islet β cells, and its expression is related to insulin secretion ability. SCRT1 is a C2H2 zinc finger transcription inhibitor, which can bind to E-box motif. The encoded protein may promote nerve differentiation and may be related to cancer with neuroendocrine characteristics. The functions of SCRT1 in islet β cells include regulating the expression and secretion of insulin and influencing the proliferation of β cells. SCRT1 may control calcineurin /NFAT signaling pathway by affecting the expression of Syt4, Notch1, Nfatc1 and Nfatc2 genes, which is an important regulator of the growth and function of β cells (PMID: 33309639). The molecular weight of SCRT1 is 36 kDa.