SDC2 Monoklonaler Antikörper

SDC2 Monoklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Maus / IgG2a

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

3A7B2

Kat-Nr. : 67088-1-PBS

Synonyme

Fibroglycan, HSPG, HSPG1, SDC2, SYND2, syndecan 2

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  WB analysis using 67088-1-Ig (same clone as 67088-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67088-1-Ig (SDC2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67088-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 67088-1-Ig (same clone as 67088-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 67088-1-Ig (SDC2 antibody) at dilution of 1:500 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67088-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 67088-1-Ig (same clone as 67088-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 67088-1-Ig (SDC2 antibody) at dilution of 1:500 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67088-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon cancer using 67088-1-Ig (same clone as 67088-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 67088-1-Ig (SDC2 antibody) at dilution of 1:500 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67088-1-PBS in a different storage buffer formulation.

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  IHC staining of human colon cancer using 67088-1-Ig (same clone as 67088-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human colon cancer tissue slide using 67088-1-Ig (SDC2 antibody) at dilution of 1:500 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67088-1-PBS in a different storage buffer formulation.

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  IHC staining of human prostate cancer using 67088-1-Ig (same clone as 67088-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue slide using 67088-1-Ig (SDC2 antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67088-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

67088-1-PBS bindet in WB, IHC, Indirect ELISA SDC2 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG2a
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: SDC2 fusion protein Ag5739
• Vollständiger Name: syndecan 2
• Berechnetes Molekulargewicht: 22 kDa
• Beobachtetes Molekulargewicht: 19 kDa, 22 and 48 kDa
• GenBank-Zugangsnummer: BC049836
• Gene symbol: SDC2
• Gene ID (NCBI): 6383
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SDC2, containing cell surface heparan sulphate proteoglycan, functions as an integral membrane protein and participates in cell proliferation, cell migration, cell adhesion and signal transduction. It has been reported that the expression level of SDC2 will be up-regulated under hypoxia condition which can induce increased release of cytokines and chemokines. Besides, methylated SDC2 can be used as a potential biomarker for early diagnosis of colon cancer. 67088-1-Ig antibody detects the 19 and 22 kDa SDC2 isoforms as well as the 48 kDa dimeric protein in SDS-PAGE.(PMID: 18803305, 23297089, 30022330, 29945573)